Languages

Antonios-Apostolos K. Tentes

MD., PhD. General Surgeon

Name: Antonios-Apostolos K. Tentes
Date of birth: August the 10th, 1953
Education: Medical School, Thessaloniki Aristotelian University, 1971-1977
Basic training: General Surgery, 1981-1985
Specific Post-medical Grants: 1985-1986

Fellowship:
Cardiothoracic surgery 1985-1987 at AHEPA General Hospital Thessaloniki Greece,
b. Hopital Broussais la Charite Paris France,
c. Queen Elizabeth Hospital Birmingham UK

Training in Surgical Oncology:
a. St. Savvas Anticancer Hospital, Athens, Greece, 1994.
b. Washington Hospital Center, 1999

Clinical experience:
Attending Surgeon, Didimotichon General Hospital, Greece, 1987-1990
Director, Surgical Department, Didimotichon General Hospital, Greece, 1990-2013
Director, Surgical Department, Program of Peritoneal Surface Malignancy, Metropolitan Hospital, N. Phaliro, Athens, Greece.

Current position: Director, Surgical Department, Program of Peritoneal Surface Malignancy, ‘’Blue Cross’’ Euromedica General clinic Thessaloniki Greece.

Membership:

  1. European Society of Surgical Oncology,
  2. Greek Society of Surgical Oncology,
  3. Surgical Society of North Greece,
  4. Thessaloniki Medical Society,
  5. International Colorectal Club,
  6. Greek Society of Colorectal Surgery,
  7. Hellenic Society for Digestive Surgery,
  8. Society for the Study of Peritoneal Carcinomatosis,
  9. Hellenic Surgical Society

Congresses-Meetings: 136
Publications-Announcements: 349
Author in Medical Books or Medical Chapters: 18

Publications:

  1. L. Kontogeorgos, P. Vassilopoulos, A. Tentes. Bilateral severe hydroureteronephrosis due to uterine prolapse. Br J Urol 1985, 57: 360-361
  2. D. Anagnostopoulos, L. Sakkas, A. A. Tentes. Small bowel fistulas in children. Ann Pediat Surg 1984, 1: 175-176
  3. G. Begossi, P. Caprino, A. A. Tentes, D. Chang, P. H. Sugarbaker. Management of peritoneal seeding from gastric cancer-Palliative gastrectomy, peritonectomy, and perioperative intraperitoneal chemotherapy. Acta Chir Austriaca 1999, 31 (suppl 155): 35-38
  4. A-A. K. Tentes, G. Tripsiannis, S. K. Markakidis, C. N. Karanikiotis, G. Tzegas, G. Georgiadis, and K. Avgidou. Peritoneal cancer index: a prognostic indicator of survival in advanced ovarian cancer. EJSO 2003, 29: 69-73
  5. Papadakis S, Mitsitsikas T, Markakidis S, Minas M, Tripsiannis G, Tentes A. A. The development of bone metastases as the first sign of metastatic spread in patients with primary solid tumours. Int Orth (SICOT) 2004, 28: 102-105
  6. Glehen O, Kwiatkowski F, Sugarbaker PH, Elias D, Levine EA, De Simone M, Barone R, Yonemura Y, Cavaliere F, Quenet F, Gutman M, Tentes A. A, Lorimier G, Bernard JL, Bereder JM, Porcheron J, Gomez-Portilla A, Shen P, Deraco M, Rat P. Cytoreductive surgery combined with perioperative intraperitoneal chemotherapy for the management of peritoneal carcinomatosis from colorectal cancer: a multi-institutional study. J Clin Oncol 2004, 22: 3284-3292
  7. A. Tentes, S. Markakidis, C. Mirelis, C. Leventis, K. Mitrousi, A. Gosev, C. Kaisas, Y. Bouyioukas, A. Xanthoulis, O. Korakianitis. Oophorectomy during surgery for colorectal carcinoma. Tech Coloproctol 2004, 8 (suppl 1): S214-S216
  8. A. A. K. Tentes. The management of peritoneal surface malignancy of colorectal cancer origin. Tech Coloproctol 2004, 8 (suppl 1): S39-S42
  9. Ch. Karanikiotis, A. A. Tentes, S. Markakidis, K. Vafiadis. Large bilateral adrenal metastases in non-small cell lung cancer. World J Surg Oncol 2004, 2: 37 doi: 10. 1186/1477-7819-2-37
  10. A. A. Tentes, C. G. Mirelis, S. K. Markakidis, K. A. Bekiaridou, I. G. Bougioukas, A. I. Xanthoulis, E. G. Tsalkidou, G. H. Zafiropoulos, I. H. Nikas. Long-term survival in advanced ovarian carcinoma following cytoreductive surgery with standard peritonectomy procedures. Int J Gynecol Cancer 2006, 16: 490-495
  11. A. A. Tentes, S. Markakidis, Ch. Karanikiotis, A. Fiska, I. Tentes, V. Manolopoulos, Th. Dimitriou. Intraarterial chemotherapy as an adjuvant treatment in locally advanced gastric cancer. Langenbeck’s Arch Surg 2006, 391: 124-129
  12. A. Xanthoulis, Ch. Mirelis, S. Markakidis, I. Bougioukas, K. Bekiaridou, E. Tsalkidou, G. Zafeiropoulos, A. A. K. Tentes. Complete cytoreduction combined with early postoperative intraperitoneal chemotherapy for ovarian carcinosarcoma: report of two cases. Gynecol Obstet Invest 2006, 62: 100-102
  13. Christodoulakis M, and Tsiftsis D, for the Hellenic Surgical Oncology Perioperative EPO Study Group. Preoperative Epoetin Alfa in colorectal surgery: a randomized, controlled study. Ann Surg Oncol 2005, 12: 1-8
  14. Papadakis SA, Babourda EC, Mitsitsikas TC, Markakidis S, Bahtis C, Koukouvis D, Tentes AA. Anti-personnel landmine injuries during peace: experience in a European country. Prehospital Disaster Med 2006, 21: 237-240
  15. A. A. Tentes, Ch. Mirelis, Ch. Karanikiotis, O. Korakianitis. Radical lymph node resection of the retroperitoneal area for left-sided colon cancer. Langenbeck’s Arch Surg 2007, 392: 155-160
  16. K. Amarantidis, K. Houhouli, K. Papatheodorou, A. Miloussis, D. Matthaios, E. Chatzaki, N. Lyrantzopoulos, A. Tsaroucha, A. Tentes, S. Kakolyris. A dose escalating study of docetaxel plus capecitabine in combination with gemcitabine in patients with advanced solid tumors. Oncol Res 2007, 16: 281-287
  17. Mirelis CG, Bekiaridou KA, Bougioukas IG, Xanthoulis AI, Tsalkidou EG, Nanou G, Vafiadis KT, Tentes AA. Long-term results of surgical treatment of hydatid disease. Acta Chir Belg 2006, 106: 684-687
  18. A. A. K. Tentes, C. G. Mirelis, I. G. Bougioukas, E. G. Tsalkidou, K. A. Bekiaridou, O. S. Korakianitis. Nuttall technique: A method for subumbilical incisional hernia repair revised. Langenbeck’s Arch Surg DOI 10.1007/s00423-007-0226-x
  19. J. Spiliotis, A. A. K. Tentes, A. Vaxevanidou, O. S. Korakianitis, A. Rogdakis, Ch. G Mirelis, A. C. Datsis, S. Kekelos. Cytoreductive surgery and intraperitoneal chemotherapy (HIPEC) in the management of peritoneal carcinomatosis. Preliminary results from two centers in Greece Balkan Union of Oncol 2007,
  20. Tentes A. A, Mirelis Ch, Bougioukas I, Xanthoulis A, Bekiaridou K, Tsalkidou E, Dimoulas A, Korakianitis O. Results of surgery for colorectal carcinoma with obstruction. Langenbeck’s Arch Surg 2008, DOI: 10: 1007/s00423-008-0307-5
  21. Spiliotis J, Tentes A. A, Vaxevanidou A, Korakianitis OS, Rogdakis A, Mirelis CG, Datsis A, Kekelos S. Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy in the management of peritoneal carcinomatosis. Preliminary results and cost from two centres in Greece. J BUON 2008, 13: 205-210.
  22. Bougioukas IG, Courcoutsakis N, Korakianitis OS, Tentes AAK, Prasopoulos P. Liver hydatid cyst perforated into the large bowel: a case report. Cases J 2009, 18, 2: 6999
  23. Amarantidis K, Xenidis N, Chelis L, Chiotis A, Tentes A, Chatzaki E, Kortsaris A, Polychronidis A, Karakitsos P, Kakolyris S. A dose escalation study of docetaxel plus capecitabine in combination with oxaliplatin in patients with advanced solid tumors. Acta Oncol 2009, Oct 20
  24. Xenidis N, Neanidis K, Amarantidis K, Dimopoulos P, Chamalidou E, Pitsiava D, Tentes A, Chatzaki E, Karakitsos P, Kakolyris S. Bi-weekly vinorelbine and gemcitabine as second-line and beyond treatment in ovarian cancer. Cancer Chemother Pharmacol 2010, 11
  25. A. A. K. Tentes, O. Korakianitis, D. Veliovits, E. Sgouridou, C. Karagiozoglou, K. Moustakas. The impact of total mesorectal excision in middle and low rectal carcinomas. J BUON 2010, 15: 56-60
  26. A. A. K. Tentes, O. S. Korakianitis, S. Kakolyris, D. Kyziridis, D. Veliovits, C. Karagiozoglou, E. Sgouridou, K. Moustakas. Cytoreductive surgery and perioperative intraperitoneal chemotherapy in recurrent ovarian cancer. Tumori 2010, 96: 411-416
  27. A. A. K. Tentes, O. S. Korakianitis, S. Kakolyris, D. Veliovits, S. Fotakis, I. Kouyioumtzi, D. Kyziridis. Differences between right- and left-sided colon carcinomas. J BUON 2010, 15: 285-289
  28. A. A. K. Tentes, O. Korakianitis, D. Kyziridis, D. Veliovits. Long-term results following potentially curative gastrectomy for gastric cancer. J BUON 2010, 15: 504-508
  29. N. Xenidis, K. Neanidis, K. Amarantidis, P. Dimopoulos, E. Chamalidou, D. Pitsiava, A. Tentes, E. Chatzaki, P. Karakitsos, S. Kakolyris. Biweekly vinorelbin and gemcitabine as second-line and beyond treatment in ovarian cancer. Cancer Chemother Pharmacol 2011, 67: 69-73
  30. A. A. K. Tentes, I. D. Spiliotis, O. S. Korakianitis, A. Vaxevanidou, D. Kyziridis. Adjuvant perioperative intraperitoneal chemotherapy in locally advanced colorectal carcinoma: preliminary results. ISRN Surgery 2011, doi: 10.5402/2011/529876
  31. Amarantidis K, Xenidis N, Chelis L, Chamalidou E, Dimopoulos P, Michailidis P, Tentes A, Deftereos S, Karanikas M, Karayiannakis A, Kakolyris S. Docetaxel plus oxaliplatin in combination with capecitabine as first-line treatment for advanced gastric cancer. Oncology 2011, 80: 359-365
  32. A. A. Tentes, S. A. Kakolyris, D. Kyziridis, C. Karamveri. Cytoreductive surgery combined with hyperthermic intraperitoneal intraoperative chemotherapy in the treatment of advanced epithelial ovarian cancer. J Oncol 2012, doi: 10.1155/2012/358341
  33. Xenidis N, Chelis L, Amarantidis K, Chamalidou E, Dimopoulos P, Courcoutsakis N, Tentes A, Chiotis A, Prasopoulos P, Kakolyris S. Docetaxel plus gemcitabine in combination with capecitabine as treatment for inoperable pancreatic cancer: a phase II study. Cancer Chemother Pharmacol 2012, 69: 477-484
  34. A. A. Tentes, O. Korakianitis, N. Pallas, C. Mavroudis, P. Sarlis, A. Liberis, A. Pagalos, S. Popidis. Peritoneal colorectal carcinomatosis treated with cytoreductive surgery and perioperative intraperitoneal chemotherapy. Surgical Science 2012, 3: 72-77
  35. N. Courcoutsakis, A. A. Tentes, E. Astrinakis, P. Zezos, P. Prasopoulos. CT-enteroclysis in the preoperative assessment of the small bowel involvement in patients with peritoneal carcinomatosis, candidates for cytoreductive surgery and hyperthermic intraperitoneal chemotherapy. Abdom Imaging 2012, DOI: 10.1007/s00261-012-9869-3
  36. A. A. K. Tentes, D. Kyziridis, S. Kakolyris, N. Pallas, G. Zorbas, O. Korakianitis, C. Mavroudis, N. Courcoutsakis, P. Prasopoulos. Preliminary results of hyperthermic intraperitoneal intraoperative chemotherapy as an adjuvant in resectable pancreatic cancer. Gastroenterol Res Pract 2012, doi: 10.1155/2012/506571
  37. Xanthoulis A, Kotsinas A, Tiniakos D, Fiska A, Tentes AA, Kyroudi A, Kittas C, Gorgoulis V. The Relationship Between E2F Family Members and Tumor Growth in Colorectal Adenocarcinomas: A Comparative Immunohistochemical Study of 100 Cases. Appl Immunohistochem Mol Morphol. 2012 Jun 7
  38. Cao C, Yan TD, Morris DL, van der Speeten K, Laurberg S, Glehen O, Link K, Piso P, Tentes AA, Deraco M, Larsen SG, Kecmanovic D, Bayón LG, Melero JT, González-Moreno S, Mahteme H, Gertsch P, Moran B, Esquivel J, Alexander R, Levine EA, Sugarbaker PH. Prospective registry on mesothelioma peritonei treatment (PROMPT): study design and rationale. Tumori. 2012 Jan-Feb;98(1):166-71. doi: 10.1700/1053.11517
  39. Korakianitis O, Andreou A, Mavroudis C, Tentes A. A. Continuous neostigmine infusion in a patient with myasthenia gravis undergoing cytoreductive surgery combined with hyperthermic intraperitoneal intraoperative chemotherapy (HIPEC). Case Study and Case Report 2012, 2: 87-90
  40. A. A. Tentes, N. Pallas, D. Kyziridis, G. Zorbas, S. Popidis, O. Korakianitis, C. Mavroudis, A. Spiridonidou. Perioperative intraperitoneal chemotherapy for advanced gastric cancer. J Solid Tumors 2012, 2:
  41. D. Veliovits, A. Fiska, G. Zorbas, A. A. Tentes. Retroperitoneal schwannomas. Am J Case Rep 2012, 13 CR 244-246
  42. A. A. Tentes, N. Pallas, D. Kyziridis, G. Zorbas, S. Popidis, O. Korakianitis, C. Mavroudis, A. Spiridonidou. Perioperative intraperitoneal chemotherapy for advanced gastric cancer. J Solid Tumors 2012, 2: 5-12
  43. A. A. Tentes, S. Kakolyris, N. Pallas, O. Korakianitis, C. Mavroudis, G. Zorbas, P. Sarlis. Preliminary results with the use of hyperthermic intraperitoneal intraoperative chemotherapy or systemic chemotherapy in high-risk colorectal cancer patients. Transl Gastrointest Cancer 2012, doi: 10.3978/j.issn 2224-4778, 2012.10.02
  44. A. A. Tentes, G. Zorbas, N. Pallas, A. Fiska. Multicystic peritoneal mesothelioma: report of a case. Am J Case Reports 2012, 13CR 262-264
  45. A.A. Tentes, N. Pallas, O. Korakianitis, C. Mavroudis, A. Spiridonidou, G. Zorbas, S. Popidis, N. Papadoniou, V. Darladima, A. Smyrnis, C. Siopis. The cost of cytoreductive surgery and perioperative intraperitoneal chemotherapy in the treatment of peritoneal malignancy in one Greek institute. J BUON 2012, 17: 776-780
  46. A. A. Tentes, S. Kakolyris, N. Pallas, O. Korakianitis, C. Mavroudis, G. Zorbas, P. Sarlis. Preliminary results with the use of hyperthermic intraperitoneal intraoperative chemotherapy or systemic chemotherapy in high-risk colorectal cancer patients. Transl Gastrointest Cancer 2012, doi: 10.3978/j.issn.2224-4778.2012.10.02
  47. Balgkouranidou I, Karayiannakis A, Matthaios D, Bolanaki H, Tripsianis G, Tentes A. A, Lianidou E, Chatzaki E, Fiska A, Lambropoulou M, Kolios G, Kakolyris S. Assessment of SOX17 DNA methylation in cell free DNA from patients with operable gastric cancer. Association with prognostic variables and survival. Clin Chem Lab Med 2013, doi 10.1515/cclm-2012-0320
  48. Stamou K, Panoussopoulos SG, Emmanouil Th, Samanta E, Tentes A. A. Chlecystocholedocholithiasis: rendezvous approach when preoperative endoscopic cholangiopancreatography is not feasible or unsuccessful. J Lapararoendoscopic and Advanced Surgical Technique. Part B, Videoscopy, 2014.
  49. Stamou K, Panoussopoulos SG, Alevizos L, Filippidis Th, Samanta E, Athanasiadis I, Tentes A. A. Totally laparoscopic resection of a retroperitoneal small round cell tumor. J Lapararoendoscopic and Advanced Surgical Technique. Part B, Videoscopy, August 2014.
  50. Mavroudis C, Alevizos L, Stamou K, Vogiatzaki T, Elefhteriadis S, Korakianitis O, Tentes A, Iatrou C. Hemodynamic monitoring during Heated Intraoperative Intraperitoneal Chemotherapy using the FloTrac/VigileoTM system. Int Surg 2015, Jan 15 (Epub ahead of print)

Research

  1. Hyperthermic intraperitoneal intraoperative chemotherapy as an adjuvant treatment after potentially curative resection of pancreatic cancer
  2. Hyperthermic intraperitoneal intraoperative chemotherapy as an adjuvant treatment after potentially curative resection of gastric cancer
  3. Hyperthermic intraperitoneal intraoperative chemotherapy as a first line adjuvant treatment after cytoreductive surgery in advanced ovarian cancer
  4. Correlation of MMP’s with gastrointestinal and gynaecologic carcinomas
  5. Intraperitoneal intraoperative hyperthermic chemotherapy in peritoneal malignancy (pseudomyxoma peritonei, peritoneal mesothelioma, gastrointestinal malignancies with peritoneal involvement, gynaecologic cancer with peritoneal involvement)
  6. Hyperthermic intaoperative intraperitoneal chemotherapy as an adjuvant treatment in locally advanced colorectal cancer
  7. The effect of epidural anesthesia and analgesia on patients undergoing maximal cytoreductive surgery in combination with HIPEC on hemostasis.
  8. Alterations of hemodynamics in patients undergoing maximal cytoreductive surgery in combination with HIPEC
  9. Identification of HURP in carcinomas with peritoneal malignancy.